J Salinet_Full Paper_CinC 2014.pdf (869.24 kB)
Distinctive Patterns of Dominant Frequency Trajectory Behaviour in Persistent Atrial Fibrillation: Spatio-temporal Characterisation
conference contribution
posted on 2015-02-05, 14:56 authored by J. L. Salinet, J. H. Tuan, A. S. M. Salinet, P. J. Stafford, G. A. Ng, F. S. SchlindweinEnhancing our understanding of the underlying AF
behaviour is a key factor to contribute towards improving
patient outcomes in special for persistent AF (persAF)
patients. In this study different signal processing and
visualisation techniques were developed and applied to
simultaneous high density sets of intracardiac
electrograms (EGMs) obtained from persAF. We
demonstrated that DF of EGMs lacked in spatiotemporal
stability, hence targeting sites of peak DF from a single
time frame is unlikely to be a reliable ablation strategy.
Tracking the centre of gravity (CGs) from the highest
dominant frequency areas (HDFAs) revealed three
distinct propagation behaviours favouring the cyclical
and local activity. The cores of the HDFAs showed to be
significantly more organised than their periphery. Realtime
implementation was shown to be feasible with the use
of Graphic Processing Units representing an innovation
that is currently being considered as part of the decision
to guide ablation therapy for persAF.
History
Citation
Computing in Cardiology 2014; 41:657-660.Author affiliation
/Organisation/COLLEGE OF SCIENCE AND ENGINEERING/Department of EngineeringSource
Computing in Cardiology, Cambridge, Mass. USAVersion
- AM (Accepted Manuscript)
Published in
Computing in Cardiology 2014; 41:657-660.issn
2325-8861Available date
2015-02-05Publisher version
http://www.cinc.org/archives/2014/pdf/0657.pdfTemporal coverage: start date
2014-09-07Temporal coverage: end date
2014-09-10Language
enAdministrator link
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