IDF2022-0579 Post COVID-19 diabetes project: Intensive cardio-renal-metabolic management for people living with type 2 diabetes (T2D)

<p>Background</p> <p>Type 2 diabetes (T2D) increases morbidity and mortality risk related to COVID-19 [1,2]. People with T2D affected by COVID-19 therefore require intensive targeting of metabolic risk factors to mitigate this risk and improve outcomes.</p> <p><br></p> <p>Aim</p> <p>The intensive multidisciplinary (MDT) project aimed to improve metabolic risk profile and emotional wellbeing in people with T2D who had severe COVID-19 by adopting a holistic approach.</p> <p><br></p> <p>Method</p> <p>The 12-month project, comprised of MDT clinics, development of referral pathways and resource building. Patients were risk-stratified and modifiable risk factors including HbA1c, weight, blood pressure, lipids and the Patient Health Questionnaire-9 depression scale (PHQ-9) were collected at baseline (first clinic appointment) and follow-up (discharge) for patients for whom at least 3-months of data was available. Linear regression assessed change from baseline for all variables.</p> <p><br></p> <p>Results</p> <p>Baseline data were collected (N = 61; male 57.4%). 56 had confirmed COVID-19. Median age was 57 years and median T2D duration was 7 years. 52.5% belonged to minority ethnic groups. A significant reduction in HbA1c, weight and PHQ-9 scores were observed at follow-up (Table 1). Use of sodium–glucose cotransporter 2 inhibitors (SGLT2i) and glucagon-like peptide-1 agonists (GLP-1RA) was associated with greater reductions in HbA1c and weight.</p> <p><br></p> <p>Conclusion</p> <p>Intensive MDT care was beneficial in improving metabolic risk profile and emotional well-being in people with T2D following COVID-19, indicating that holistic approach targeting multiple risk factors improves physical and psychological outcomes for people with T2D.</p>