Appendix III: Crossover activity

dataset

posted on 2020-06-02, 10:03 authored by Ihthisham AliIhthisham Ali

PhD thesis: PRDM9 Diversity, Recombination Landscapes and Childhood Leukaemia by Ihthisham Ali

Appendix III contains hotspot activity analysis data on DNA3 and AA hotspots in a MHCII sub-region. These data is indicative of the local recombination profile in the MHCII and provides confirmatory evidence for the differential activation of PRDM9 A and a subset of Ct alleles for these two hotspots. Additionally, these data provide fine-scale information on the morphology of the AA hotspot.

A. DNA3 hotspot CO activity data

B. DNA3 hotspot Chi-Squared Test

C. AA hotspot CO activity data

D. AA hotspot d257 (20) breakpoint mapping

E. AA hotspot d257 (20) hotspot morphology graph data