Supplemental Material Am J Physiol Regul Integr Comp Physiol 2024

The study tested the hypothesis that continuous measurements of muscle sympathetic nervous activity (MSNA) are associated with changes in cerebral blood flow as measured with transcranial Doppler ultrasound in the middle cerebral artery (MCAv). Partial coherence analysis was adopted to test this association and the the response of MCAv to step changes in arterial blood pressure and MSNA were described, the latter for the first time.