Lay summary and brief biological or clinical significance
A human cancer cell is shown in the act of dividing. Understanding the process of cancer cell
division and the molecular pathways involved allows us to identify new
strategies for the selective killing of rapidly dividing cancer cells.
Technical summary
Human HeLa cervical carcinoma cells were fixed in ice-cold methanol and stained with antibodies against α-tubulin to detect microtubules (red) and CenpA to detect kinetochores (green). DNA was stained with Hoechst 33258 (blue) to identify the condensed chromosomes.