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A Multimodality Hybrid Gamma-Optical Camera for Intraoperative Imaging.pdf (6.75 MB)

A Multimodality Hybrid Gamma-Optical Camera for Intraoperative Imaging

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posted on 2017-05-24, 10:30 authored by John E. Lees, Sarah L. Bugby, Mohammed S. Alqahtani, Layal K. Jambi, Numan S. Dawood, William R. McKnight, Aik H. Ng, Alan C. Perkins
The development of low profile gamma-ray detectors has encouraged the production of small field of view (SFOV) hand-held imaging devices for use at the patient bedside and in operating theatres. Early development of these SFOV cameras was focussed on a single modality-gamma ray imaging. Recently, a hybrid system-gamma plus optical imaging-has been developed. This combination of optical and gamma cameras enables high spatial resolution multi-modal imaging, giving a superimposed scintigraphic and optical image. Hybrid imaging offers new possibilities for assisting clinicians and surgeons in localising the site of uptake in procedures such as sentinel node detection. The hybrid camera concept can be extended to a multimodal detector design which can offer stereoscopic images, depth estimation of gamma-emitting sources, and simultaneous gamma and fluorescence imaging. Recent improvements to the hybrid camera have been used to produce dual-modality images in both laboratory simulations and in the clinic. Hybrid imaging of a patient who underwent thyroid scintigraphy is reported. In addition, we present data which shows that the hybrid camera concept can be extended to estimate the position and depth of radionuclide distribution within an object and also report the first combined gamma and Near-Infrared (NIR) fluorescence images.

History

Citation

Sensors, 2017, 17 (3), 554

Author affiliation

/Organisation/COLLEGE OF SCIENCE AND ENGINEERING/Department of Physics and Astronomy

Version

  • VoR (Version of Record)

Published in

Sensors

Publisher

MDPI

eissn

1424-8220

Acceptance date

2017-03-07

Copyright date

2017

Available date

2017-05-24

Publisher version

http://www.mdpi.com/1424-8220/17/3/554

Language

en

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