A short history of heme dioxygenases: rise, fall and rise again
journal contributionposted on 2017-03-28, 13:57 authored by Emma L. Raven
It is well established that there are two different classes of enzymes—tryptophan 2,3-dioxygenase (TDO) and indoleamine 2,3-dioxygenase (IDO)—that catalyse the O2-dependent oxidation of l-tryptophan to N-formylkynurenine. But it was not always so. This perspective presents a short history of the early TDO and IDO literature, the people that were involved in creating it, and the legacy that this left for the future.
CitationJournal of Biological Inorganic Chemistry, 2017, 22 (2), pp. 175–183
Author affiliation/Organisation/COLLEGE OF SCIENCE AND ENGINEERING/Department of Chemistry
- VoR (Version of Record)