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A short history of heme dioxygenases: rise, fall and rise again

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journal contribution
posted on 2017-03-28, 13:57 authored by Emma L. Raven
It is well established that there are two different classes of enzymes—tryptophan 2,3-dioxygenase (TDO) and indoleamine 2,3-dioxygenase (IDO)—that catalyse the O2-dependent oxidation of l-tryptophan to N-formylkynurenine. But it was not always so. This perspective presents a short history of the early TDO and IDO literature, the people that were involved in creating it, and the legacy that this left for the future.

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Citation

Journal of Biological Inorganic Chemistry, 2017, 22 (2), pp. 175–183

Author affiliation

/Organisation/COLLEGE OF SCIENCE AND ENGINEERING/Department of Chemistry

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  • VoR (Version of Record)

Published in

Journal of Biological Inorganic Chemistry

Publisher

Springer Verlag

issn

0949-8257

eissn

1432-1327

Acceptance date

2016-11-10

Copyright date

2017

Available date

2017-03-28

Publisher version

https://link.springer.com/article/10.1007/s00775-016-1412-5

Language

en

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