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journal contribution
posted on 2020-04-21, 08:26authored bySudesna Chatterjee, Melanie J Davies
A cluster analysis of five independent Swedish cohorts of people with diabetes mellitus has identified five clusters of classification based on age at diagnosis, BMI, HbA1c autoantibodies and markers of insulin resistance. Patients in each of the clusters have specific disease characteristics and unique risk profiles for complications from diabetes mellitus.
Funding
The authors acknowledge support from the National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care – East Midlands (NIHR CLAHRC – EM), the Leicester Clinical Trials Unit, and the NIHR Leicester-Loughborough Diet, Lifestyle and Physical Activity Biomedical Research Centre, which is a partnership between University Hospitals of Leicester NHS Trust, Loughborough University and the University of Leicester.
History
Citation
Chatterjee, Sudesna, and Melanie J. Davies. "Accurate diagnosis of diabetes mellitus and new paradigms of classification." Nature Reviews Endocrinology, vol. 14, no. 7, 2018, p. 386+.
This is a comment on "Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables." Lancet Diabetes Endocrinol. 2018 May;6(5):361-369.