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Aircraft noise and cardiovascular morbidity and mortality near Heathrow Airport A case-crossover study.pdf (4.54 MB)

Aircraft noise and cardiovascular morbidity and mortality near Heathrow Airport: A case-crossover study

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posted on 2023-08-10, 13:45 authored by N Itzkowitz, X Gong, G Atilola, G Konstantinoudis, K Adams, C Jephcote, J Gulliver, AL Hansell, M Blangiardo
Aircraft noise causes annoyance and sleep disturbance and there is some evidence of associations between long-term exposures and cardiovascular disease (CVD). We investigated short-term associations between previous day aircraft noise and cardiovascular events in a population of 6.3 million residing near Heathrow Airport using a case-crossover design and exposure data for different times of day and night. We included all recorded hospitalisations (n = 442,442) and deaths (n = 49,443) in 2014–2018 due to CVD. Conditional logistic regression was used to estimate the ORs and adjusted for NO2 concentration, temperature, and holidays. We estimated an increase in risk for 10 dB increment in noise during the previous evening (Leve OR = 1.007, 95% CI 0.999–1.015), particularly from 22:00–23:00 h (OR = 1.007, 95% CI 1.000–1.013), and the early morning hours 04:30–06:00 h (OR = 1.012, 95% CI 1.002–1.021) for all CVD admissions, but no significant associations with day-time noise. There was effect modification by age-sex, ethnicity, deprivation, and season, and some suggestion that high noise variability at night was associated with higher risks. Our findings are consistent with proposed mechanisms for short-term impacts of aircraft noise at night on CVD from experimental studies, including sleep disturbance, increases in blood pressure and stress hormone levels and impaired endothelial function.

Funding

Reduced noise Impacts of Short-Term Aircraft Noise and Cardiovascular Outcomes (RISTANCO)

NIHR Evaluation Trials and Studies Coordinating Centre

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MRC-PHE Centre for Environment and Health

Medical Research Council

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History

Citation

Nicole Itzkowitz, Xiangpu Gong, Glory Atilola, Garyfallos Konstantinoudis, Kathryn Adams, Calvin Jephcote, John Gulliver, Anna L Hansell, Marta Blangiardo, Aircraft noise and cardiovascular morbidity and mortality near Heathrow Airport: A case-crossover study, Environment International, Volume 177, 2023, 108016, ISSN 0160-4120, https://doi.org/10.1016/j.envint.2023.108016.

Version

  • VoR (Version of Record)

Published in

Environment International

Volume

177

Pagination

108016

Publisher

Elsevier BV

issn

0160-4120

eissn

1873-6750

Acceptance date

2023-06-01

Copyright date

2023

Available date

2023-08-10

Spatial coverage

Netherlands

Language

eng

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