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Application of molecularly imprinted polymer nanoparticles for degradation of the bacterial autoinducer N-hexanoyl homoserine lactone.

journal contribution
posted on 2019-03-27, 17:10 authored by J Garcia Lopez, EV Piletska, MJ Whitcombe, J Czulak, SA Piletsky
A novel bacterial quorum quenching system is presented. For the first time the degradation of N-l-hexanoyl homoserine lactone (C6-AHL), a Gram-negative quorum sensing autoinducer, has been enhanced using molecularly imprinted nanoparticles (MIP NPs) which were prepared using transition state analogue of the γ-lactone ring hydrolysis as template.

History

Citation

Chemical Communications, 2019, 55, 2664-2667

Author affiliation

/Organisation/COLLEGE OF SCIENCE AND ENGINEERING/Department of Chemistry

Version

  • AM (Accepted Manuscript)

Published in

Chemical Communications

Publisher

Royal Society of Chemistry

eissn

1364-548X

Acceptance date

2019-02-04

Copyright date

2019

Publisher version

https://pubs.rsc.org/en/Content/ArticleLanding/2019/CC/C8CC07685E#!divAbstract

Notes

Electronic supplementary information (ESI) available: The experimental protocols, synthesis of TSA and NPs and methods of characterisation of NPs. See DOI: 10.1039/c8cc07685e;The file associated with this record is under embargo until 12 months after publication, in accordance with the publisher's self-archiving policy. The full text may be available through the publisher links provided above.

Language

en

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