Association between frailty and hospital-related adverse events in older hospitalised patients: a systematic literature review protocol
Introduction
Research indicates that older hospitalised individuals are more susceptible to hospital adverse events (AEs). Frailty is a syndrome marked by increased vulnerability, sudden and severe health changes and the risk of adverse outcomes. The majority of the available research puts a limited emphasis on those who live with frailty and examines the relationship between age alone and the occurrence of AEs. This review investigates the association between frailty and the likelihood of hospital AE occurrences in hospitalised older patients.
Methods and analysis
The proposed systematic review will search Ovid MEDLINE, CINAHL, Scopus and Web of Science databases. Studies that published original data in English using any methodology will be included. A manual search of the final included studies reference list will be made to identify studies that meet the inclusion criteria. If feasible, a meta-analysis will be conducted using the R statistical programme, and results will be visually presented using a forest plot. If there is high heterogeneity and a meta-analysis is not feasible, a narrative synthesis and analysis guided by Cochrane criteria will be conducted, and results will be presented in appropriate tables and figures.
Ethics and dissemination
No ethical approval will be obtained for this review since it will use secondary published data. The systematic review’s results will be published in a peer-reviewed frailty and geriatrics care-related journal and disseminated in conferences, congresses and scientific meetings.
Funding
Imam Abdulrahman bin Faisal University
History
Citation
Alotaibi F, Alshibani A, Banerjee J, et alAssociation between frailty and hospital-related adverse events in older hospitalised patients: a systematic literature review protocolBMJ Open 2025;15:e094422. doi: 10.1136/bmjopen-2024-094422Author affiliation
College of Life Sciences Population Health SciencesVersion
- VoR (Version of Record)
Published in
BMJ OpenVolume
15Issue
2Pagination
e094422 - e094422Publisher
BMJissn
2044-6055eissn
2044-6055Acceptance date
2025-01-24Copyright date
2025Available date
2025-03-07Publisher DOI
Spatial coverage
EnglandLanguage
enPublisher version
Deposited by
Professor Brad ManktelowDeposit date
2025-02-20Rights Retention Statement
- No