3677.pdf (227.06 kB)
Download fileCalcium signalling in bacteria
journal contribution
posted on 2006-06-16, 10:54 authored by V. Norris, Susan Grant, Primrose P.E. Freestone, J. Canvin, F. N. Sheikh, I. Toth, M. Trinei, K. Modha, Robert I. Norman[First paragraph] In eukaryotic cells, variations in the levels of cytosolic free
calcium regulate processes as important and disparate as chemotaxis, chromosome segregation, fertilization, ion transport,
muscle contraction, passage through cell cycle transition
points, proteolysis, secretion, and substrate uptake (7). Cytosolic free calcium concentration is tightly controlled by the
action of specific pumps and channels in the plasma membrane
and subcellular organelles (8, 83). Response to increased cytosolic free calcium concentration is mediated by either direct
binding to calcium-sensitive enzymes, such as protein kinase C
(49) and calpain (72), or activation of a protein transducer,
such as calmodulin (15).
History
Citation
Journal of Bacteriology, 1996, 178(13), pp.3677-3682Version
- VoR (Version of Record)