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Characterizing the Contribution of Dependent Features in XAI Methods

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posted on 2025-01-09, 09:46 authored by Ahmed SalihAhmed Salih, Ilaria Boscolo Galazzo, Zahra Raisi-Estabragh, Steffen E Petersen, Gloria Menegaz, Petia Radeva
Explainable Artificial Intelligence (XAI) provides tools to help understanding how AI models work and reach a particular decision or outcome. It helps to increase the interpretability of models and makes them more trustworthy and transparent. In this context, many XAI methods have been proposed to make black-box and complex models more digestible from a human perspective. However, one of the main issues that XAI methods have to face especially when dealing with a high number of features is the presence of multicollinearity, which casts shadows on the robustness of the XAI outcomes, such as the ranking of informative features. Most of the current XAI methods either do not consider the collinearity or assume the features are independent which, in general, is not necessarily true. Here, we propose a simple, yet useful, proxy that modifies the outcome of any XAI feature ranking method allowing to account for the dependency among the features, and to reveal their impact on the outcome. The proposed method was applied to SHAP, as an example of XAI method which assume that the features are independent. For this purpose, several models were exploited for a well-known classification task (males versus females) using nine cardiac phenotypes extracted from cardiac magnetic resonance imaging as features. Principal component analysis and biological plausibility were employed to validate the proposed method. Our results showed that the proposed proxy could lead to a more robust list of informative features compared to the original SHAP in presence of collinearity.

Funding

Long-term effects of SARS-CoV-2 infection on cardiovascular morbidity and its determinants

British Heart Foundation

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Fondazione CariVerona (Grant Number: 2018.0855.2019)

National Institute for Health and Care Research

Academic Clinical Lectureship

Broken bones and broken hearts: Relationships between osteoporosis and cardiovascular structure and function in UK Biobank (Dr Zahra Raisi Estabragh)

British Heart Foundation

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European Union's Horizon 2020 Research and Innovation Programme

euCanSHare (Grant Number: 825903)

London Medical Imaging and Artificial Intelligence Centre for Value Based Healthcare (Grant Number: AI4VBH)

Data to Early Diagnosis and Precision Medicine

Industrial Strategy Challenge

U.K. Research and Innovation

History

Author affiliation

College of Life Sciences Population Health Sciences

Version

  • AM (Accepted Manuscript)

Published in

IEEE Journal of Biomedical and Health Informatics

Volume

28

Issue

11

Pagination

6466 - 6473

Publisher

Institute of Electrical and Electronics Engineers (IEEE)

issn

2168-2194

eissn

2168-2208

Copyright date

2024

Available date

2025-01-09

Spatial coverage

United States

Language

eng

Deposited by

Dr Ahmed Salih

Deposit date

2024-12-03

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