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Comparative Evaluation of Neural Networks and Transfer Learning for Predicting Mechanical Properties of 3D‐Printed Bone Scaffolds

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posted on 2025-06-30, 11:27 authored by S Mohsen Zahedi, Aboozar Taherkhani, Reza BaseriniaReza Baserinia, S Abolfazl Zahedi, Hafiz Muhammad Asad Ali, Meisam Abdi

Due to the complexity of bone structures, influenced by factors such as injuries, defects, age, and health conditions, creating accurate 3D personalized scaffolds is challenging and requires extensive trial‐and‐error. To ensure high‐quality bespoke scaffolds, three key mechanical parameters—volume fraction, Poisson's ratio, and elastic modulus—must be accurately calculated during surgery. This research proposed the idea of applying convolutional neural networks (CNNs) and Transfer Learning (TL) to predict the volume fraction, Poisson's ratio and elastic modulus of medical bone scaffolds. Deep neural networks require extensive training data, but obtaining a large volume of labelled data is often challenging. In this study, a comprehensive dataset is generated by the parametric implicit equation of Body Centered Cubic (BCC) lattice structure to train deep neural networks. The result shows that the CNNs adopt better in comparison to Transfer Learning Resnet‐50, Resnet‐15 and Resnet‐34 for predicting the fundamental properties of medical bone implants. The Resnet‐50 model demonstrates the highest MEA (Mean Absolute Error) in volume fraction (1.382), Poisson's ratio (0.006), and elastic modulus (12.551), while the CNN model shows the lowest values, with volume fraction MEA of 0.348, Poisson's ratio of 0.003, and elastic modulus of 4.853. The research findings can be used by medical surgeons and biomechanical engineers to calculate the mechanical properties of 3D scaffolds.

History

Author affiliation

College of Science & Engineering Engineering

Version

  • VoR (Version of Record)

Published in

Macromolecular Materials and Engineering

Publisher

Wiley

issn

1438-7492

eissn

1439-2054

Copyright date

2025

Available date

2025-06-30

Language

en

Deposited by

Dr Reza Baserinia

Deposit date

2025-06-03

Data Access Statement

The data that support the findings of this study are available from the corresponding author upon reasonable request.

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