Conditional crude probabilities of death for English cancer patients

Introduction Cancer survival statistics are typically reported using measures discounting the impact of other cause mortality, such as net survival. This is a hypothetical measure and is interpreted as excluding the possibility of cancer patients dying from other causes. Crude probability of death partitions the allcause probability of death into deaths from cancer and other causes. Methods The National Cancer Registration and Analysis Service is the single cancer registry for England. In 2006-2015, 1,590,477 malignant tumours were diagnosed for breast, colorectal, lung, melanoma and prostate in adults. We used a relative survival framework, with a period approach, providing estimates for up to 10-year survival. Mortality was partitioned into deaths due to cancer or other causes. Unconditional and conditional (on surviving 1- and 5-years) crude probability of death were estimated for the five cancers. Results Elderly patients who survived for a longer period before dying were more likely to die from other causes of death (except for lung cancer). For younger patients, deaths were almost entirely due to the cancer. Discussion There are different measures of survival, each with their own strength and limitations. Careful choices of survival measures are needed for specific scenarios to maximise the understanding of the data.