Decreased striatal RGS2 expression is neuroprotective in Huntington's disease (HD) and exemplifies a compensatory aspect of HD-induced gene regulation.
journal contribution
posted on 2012-10-24, 08:54 authored by T. Seredenina, O. Gokce, R. Luthi-CarterThe molecular phenotype of Huntington's disease (HD) is known to comprise highly reproducible changes in gene expression involving striatal signaling genes. Here we test whether individual changes in striatal gene expression are capable of mitigating HD-related neurotoxicity.
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PLOS ONE, 2011, 6 (7), pp. e22231-e22231Version
- VoR (Version of Record)
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PLOS ONEPublisher
Public Library of Scienceeissn
1932-6203Copyright date
2011Available date
2012-10-24Publisher DOI
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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0022231Language
engAdministrator link
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