Editorial: Antimicrobial Peptides and Complement - Maximising the Inflammatory Response..pdf (76.55 kB)
Editorial: Antimicrobial Peptides and Complement - Maximising the Inflammatory Response.
journal contribution
posted on 2016-05-26, 12:57 authored by Cordula M. StoverStriking commonalities in the roles of complement and antimicrobial peptides have recently been reported; their abilities to apply selection pressures on a bacterial population in the bloodstream (1), to contribute to enhanced phagocytosis of opsonized bacteria (2), and to interactively determine skin microbiome (3). Evolutionary roots for complement proteins and antimicrobial peptides are ancient (4). Predating the avenue of somatic recombination, antimicrobial peptides and complement have further emerged as modulators of cell activities that are part of the adaptive immune response. Therefore, antimicrobial peptides and complement were logical contenders for a focused analysis to distil from a wide complexity a range of overlapping and distinct activities that could serve to maximize local and systemic inflammatory responses. [Opening paragraph]
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Frontiers in Immunology, 2015, 6:491Author affiliation
/Organisation/COLLEGE OF MEDICINE, BIOLOGICAL SCIENCES AND PSYCHOLOGY/School of Medicine/Department of Infection, Immunity and InflammationVersion
- VoR (Version of Record)
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Frontiers in ImmunologyPublisher
Frontiers Mediaeissn
1664-3224Copyright date
2015Available date
2016-05-26Publisher DOI
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http://journal.frontiersin.org/article/10.3389/fimmu.2015.00491/fullLanguage
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