posted on 2019-08-23, 15:59authored byTA Eyre, HS Walter, S Iyengar, G Follows, M Cross, CP Fox, A Hodson, J Coats, S Narat, N Morley, MJS Dyer, GP Collins
Mantle cell lymphoma (MCL), an aggressive B-cell malignancy accounting for 6% of non-Hodgkin lymphomas, remains incurable with standard therapy. Despite the approval of bortezomib,1 temsirolimus,2 lenalidomide,3 ibrutinib4 and acalabrutinib,5 patients with relapsed, refractory MCL have a survival of 2 years.