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Electrophilic fluorination using a hypervalent iodine reagent derived from fluoride
journal contributionposted on 2015-10-29, 13:19 authored by Gemma Geary, Eric G. Hope, Kuldip Singh, Alison M. Stuart
The air and moisture stable fluoroiodane 8, readily prepared on a 6 g scale by nucleophilic fluorination of the hydroxyiodane 7 with TREAT-HF, has been used as an electrophilic fluorinating reagent for the first time to monofluorinate 1,3-ketoesters and difluorinate 1,3-diketones in good isolated yields.
CitationChemical Communications, 2013, 49 (81), pp. 9263-9265
Author affiliation/Organisation/COLLEGE OF SCIENCE AND ENGINEERING/Department of Chemistry
- AM (Accepted Manuscript)