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Enantioselective copper catalysed, direct functionalisation of allenes via allyl copper intermediates
journal contribution
posted on 2019-09-18, 14:32 authored by Alexander P. Pulis, Kay Yeung, David J. ProcterThe direct functionalisation of allenes under copper catalysis enables efficient access to enantioenriched, densely functionalised molecules. In this review we explore the breadth and depth of a versatile reaction manifold, which involves the element-cupration of allenes to generate allyl copper intermediates that are subsequently coupled with diverse arrays of electrophiles.
Funding
We thank the University of Manchester (President's Scholarship to K. Y. and Lectureship to A. P. P.), the SCI (Scholarship to K. Y.), and the EPSRC (Studentships to K. Y. and Established Career Fellowship to D. J. P.). All publication charges for this article have been paid for by the Royal Society of Chemistry
History
Citation
Chemical Science, 2017, 8 (8), pp. 5240-5247Author affiliation
/Organisation/COLLEGE OF SCIENCE AND ENGINEERING/Department of ChemistryVersion
- VoR (Version of Record)
