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Exercise-induced Biochemical Modifications in Muscle in Chronic Kidney Disease: Occult Acidosis as a Potential Factor Limiting the Anabolic Effect of Exercise

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posted on 2011-03-08, 15:02 authored by Emma L. Clapp, Alan Bevington
There is growing evidence that exercise may be beneficial in limiting or reversing problems related to chronic kidney disease (CKD); but exercise therapy has had limited success in increasing lean body mass, implying that metabolic abnormalities in muscle during CKD may limit the anabolic effectiveness of exercise. This short review summarizes evidence that exercise may result in a transient worsening of the pre-existing metabolic acidosis that occurs in these patients; a metabolic defect that may reverse the normal anabolic effects of exercise.

History

Citation

Journal of Renal Nutrition, 2011, 21 (1), pp. 57-60.

Published in

Journal of Renal Nutrition

Publisher

Elsevier on behalf of the Council on Renal Nutrition of the National Kidney Foundation and the International Society of Renal Nutrition and Metabolism

issn

1051-2276

Copyright date

2011

Available date

2011-03-08

Publisher version

http://www.sciencedirect.com/science/article/pii/S1051227610002980

Language

en

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