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Factors underlying restricted crossover localization in barley meiosis

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journal contribution
posted on 2015-02-02, 12:07 authored by James D. Higgins, Kim Osman, Gareth H. Jones, F. Chris H. Franklin
Meiotic recombination results in the formation of cytological structures known as chiasmata at the sites of genetic crossovers (COs). The formation of at least one chiasma/CO between homologous chromosome pairs is essential for accurate chromosome segregation at the first meiotic division as well as for generating genetic variation. Although DNA double-strand breaks, which initiate recombination, are widely distributed along the chromosomes, this is not necessarily reflected in the chiasma distribution. In many species there is a tendency for chiasmata to be distributed in favored regions along the chromosomes, whereas in others, such as barley and some other grasses, chiasma localization is extremely pronounced. Localization of chiasma to the distal regions of barley chromosomes restricts the genetic variation available to breeders. Studies reviewed herein are beginning to provide an explanation for chiasma localization in barley. Moreover, they suggest a potential route to manipulating chiasma distribution that could be of value to plant breeders.

Funding

Biotechnology and Biological Sciences Research Council (Grant BB/F019351/1).

History

Citation

Annual Review of Genetics, 2014, 48, pp. 29-47 (19)

Author affiliation

/Organisation/COLLEGE OF MEDICINE, BIOLOGICAL SCIENCES AND PSYCHOLOGY/School of Biological Sciences/Department of Biology

Version

  • AO (Author's Original)

Published in

Annual Review of Genetics

issn

0066-4197

eissn

1545-2948

Copyright date

2014

Available date

2015-02-02

Publisher version

http://www.annualreviews.org/doi/abs/10.1146/annurev-genet-120213-092509

Language

en

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