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Functional analysis of altered Tenascin isoform expression in breast cancer
journal contribution
posted on 2012-10-24, 09:00 authored by R. A. Alcock, J. H. Pringle, J. A. Shaw, D. L. Holliday, M. Allen, R. A. Walker, J. L. JonesBackground:
Cellular interactions with the extracellular matrix (ECM) control many aspects of cell function. The complex ECM protein Tenascin-C (TN), which exists as multiple isoforms, is upregulated in breast cancer. We previously have identified a change in the TN isoform profile in breast cancer, with detection of two additional isoforms — TN16 and TN14/16 — not seen in normal breast [1]. The purpose of this study was to investigate directly the effects of these tumour-associated TNC isoforms on breast cancer cell behaviour.
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Citation
Breast Cancer Research, 2006, 8(Suppl 2):P20Published in
Breast Cancer ResearchPublisher
BioMed Centralissn
1465-5411Available date
2012-10-24Publisher DOI
Publisher version
http://www.breast-cancer-research.com/content/8/S2/P20Language
EnglishAdministrator link
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