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Glomerular disease: Sugars and immune complex formation in IgA nephropathy

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posted on 2010-01-25, 16:48 authored by Jonathan Barratt, Frank Eitner
Mesangial deposition of IgA is the principal trigger for the development of glomerulonephritis in IgA nephropathy (IgAN). Recurrence of IgA deposition in the majority of recipients of renal allografts suggests that this IgA is derived from a circulating pool of pathogenic IgA molecules.

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Citation

Nature Reviews Nephrology, 2009, 5 (11), pp. 612-614.

Published in

Nature Reviews Nephrology

Publisher

Nature Publishing Group

issn

1759-5061

Copyright date

2009

Available date

2010-01-25

Publisher version

http://www.nature.com/nrneph/journal/v5/n11/full/nrneph.2009.165.html

Language

en

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