Handheld Optical Coherence Tomography in a Young Infant With Albinism and Fovea Plana.
journal contributionposted on 2020-10-12, 15:34 authored by Sohaib R Rufai, Helena Lee, Irene Gottlob
We present handheld optical coherence tomography (OCT) diagnosis of Grade 4 foveal hypoplasia (fovea plana) in a 28-day-old infant with albinism. Grade 4 foveal hypoplasia is characterized by the absence of the foveal pit, absence of outer segment lengthening, and absence of outer nuclear layer widening. Binocular visual acuity at 58 months follow-up was 1.2 logarithm of the minimal angle of resolution (logMAR). We describe our handheld OCT acquisition protocol and compare the morphological features with a healthy, age-matched control subject.
This work was supported by the Medical Research Council(MRC), UK (grant nos.: MR/N004566/1 and MR/J004189/1); Fight for Sight, UK (grant nos.: 24NN181 and 5009/5010); Ulverscroft Foundation, UK; Nystagmus Network, UK. Dr Sohaib Rufaiis funded by a National Institute for Health Research (NIHR) Doctoral Fellowshipfor this project. The funding organizationshad no role in the design or conduct of this research. This report presents independent research funded by the National Institute for Health Research (NIHR), MRC, Fight for Sight, Ulverscroft Foundation and Nystagmus Network.
CitationJournal of Neuro-Ophthalmology: September 11, 2020 - Volume doi: 10.1097/WNO.0000000000001094
Author affiliationDepartment of Health Sciences, University of Leicester
- AM (Accepted Manuscript)