journal.pone.0070172.pdf (2.35 MB)
Inter-Individual and Inter-Strain Variations in Zebrafish Locomotor Ontogeny
journal contributionposted on 2015-07-14, 14:24 authored by M. Lange, F. Neuzeret, B. Fabreges, C. Froc, S. Bedu, L. Bally-Cuif, William H. J. Norton
Zebrafish exhibit remarkable alterations in behaviour and morphology as they develop from early larval stages to mature adults. In this study we compare the locomotion parameters of six common zebrafish strains from two different laboratories to determine the stability and repeatability of these behaviours. Our results demonstrate large variability in locomotion and fast swim events between strains and between laboratories across time. These data highlight the necessity for careful, strain-specific controls when analysing locomotor phenotypes and open up the possibility of standardising the quantification of zebrafish behaviour at multiple life stages.
CitationPLoS ONE, 2013, 8(8) : e70172
Author affiliation/Organisation/COLLEGE OF MEDICINE, BIOLOGICAL SCIENCES AND PSYCHOLOGY/School of Biological Sciences/Department of Biology
- VoR (Version of Record)