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Interdisciplinary perspectives on multimorbidity in Africa: Developing an expanded conceptual model

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posted on 2024-09-30, 11:23 authored by Justin Dixon, Ben Morton, Misheck J Nkhata, Alan Silman, Ibrahim G Simiyu, Stephen A Spencer, Myrna Van Pinxteren, Christopher Bunn, Claire Calderwood, Clare IR Chandler, Edith Chikumbu, Amelia C Crampin, John R Hurst, Modou Jobe, Andre Pascal Kengne, Naomi S Levitt, Mosa Moshabela, Mayowa Owolabi, Nasheeta Peer, Nozgechi Phiri, Sally J Singh, Tsaone Tamuhla, Mandikudza Tembo, Nicki Tiffin, Eve Worrall, Nateiya M Yongolo, Gift T Banda, Fanuel Bickton, Abbi-Monique Mamani Bilungula, Edna Bosire, Marlen S Chawani, Beatrice Chinoko, Mphatso Chisala, Jonathan Chiwanda, Sarah Drew, Lindsay Farrant, Rashida A Ferrand, Mtisunge Gondwe, Celia L Gregson, Richard Harding, Dan Kajungu, Stephen Kasenda, Winceslaus Katagira, Duncan Kwaitana, Emily Mendenhall, Adwoa Bemah Boamah Mensah, Modai Mnenula, Lovemore Mupaza, Maud Mwakasungula, Wisdom Nakanga, Chiratidzo Ndhlovu, Kennedy Nkhoma, Owen Nkoka, Edwina Addo Opare-Lokko, Jacob Phulusa, Alison Price, Jamie Rylance, Charity Salima, Sangwani Salimu, Joachim Sturmberg, Elizabeth Vale, Felix Limbani

Multimorbidity is an emerging challenge for health systems globally. It is commonly defined as the co-occurrence of two or more chronic conditions in one person, but its meaning remains a lively area of academic debate, and the utility of the concept beyond high-income settings is uncertain. This article presents the findings from an interdisciplinary research initiative that drew together 60 academic and applied partners working in 10 African countries to answer the questions: how useful is the concept of multimorbidity within Africa? Can the concept be adapted to context to optimise its transformative potentials? During a three-day concept-building workshop, we investigated how the definition of multimorbidity was understood across diverse disciplinary and regional perspectives, evaluated the utility and limitations of existing concepts and definitions, and considered how to build a more context-sensitive, cross-cutting description of multimorbidity. This iterative process was guided by the principles of grounded theory and involved focus- and whole-group discussions during the workshop, thematic coding of workshop discussions, and further post-workshop development and refinement. Three thematic domains emerged from workshop discussions: the current focus of multimorbidity on constituent diseases; the potential for revised concepts to centre the priorities, needs, and social context of people living with multimorbidity (PLWMM); and the need for revised concepts to respond to varied conceptual priorities amongst stakeholders. These themes fed into the development of an expanded conceptual model that centres the catastrophic impacts multimorbidity can have for PLWMM, families and support structures, service providers, and health systems.

Funding

Multimorbidity-associated emergency hospital admissions: a “screen and link” strategy to improve outcomes for high-risk patients in sub-Saharan Africa

National Institute for Health Research

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NIHR Leicester Biomedical Research Centre

Multimorbidity and Knowledge Architectures: An Interdisciplinary Global Health Collaboration

Wellcome Trust

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Alleviating the Burden of Chronic Respiratory Diseases in Low- and Middle-Income Countries: Developing a Pulmonary Rehabilitation Research Network

Academy of Medical Sciences

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History

Author affiliation

College of Life Sciences Respiratory Sciences

Version

  • VoR (Version of Record)

Published in

PLOS Global Public Health

Volume

4

Issue

7

Pagination

e0003434

Publisher

Public Library of Science (PLoS)

issn

2767-3375

eissn

2767-3375

Copyright date

2024

Available date

2024-09-30

Editors

Amaral AFS

Spatial coverage

United States

Language

en

Deposited by

Mrs Louise Thompson

Deposit date

2024-08-29

Data Access Statement

Source materials have been deidentified and deposited in Harvard Dataverse. These include the rapporteur notes from the concept-building workshop upon which this article is based and are available upon reasonable request. The DOI for the source materials in the repository are: https://doi.org/10.7910/DVN/YVO7SW.

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