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LabPipe: an extensible bioinformatics toolkit to manage experimental data and metadata

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posted on 2021-01-05, 10:25 authored by B Zhao, L Bryant, R Cordell, M Wilde, D Salman, D Ruszkiewicz, W Ibrahim, A Singapuri, T Coats, E Gaillard, C Beardsmore, T Suzuki, L Ng, N Greening, P Thomas, P Monks, C Brightling, S Siddiqui, RC Free
Background: Data handling in clinical bioinformatics is often inadequate. No freely available tools provide straightforward approaches for consistent, flexible metadata collection and linkage of related experimental data generated locally by vendor software. Results: To address this problem, we created LabPipe, a flexible toolkit which is driven through a local client that runs alongside vendor software and connects to a light-weight server. The toolkit allows re-usable configurations to be defined for experiment metadata and local data collection, and handles metadata entry and linkage of data. LabPipe was piloted in a multi-site clinical breathomics study. Conclusions: LabPipe provided a consistent, controlled approach for handling metadata and experimental data collection, collation and linkage in the exemplar study and was flexible enough to deal effectively with different data handling challenges.

History

Citation

BMC Bioinformatics 21, 556 (2020). https://doi.org/10.1186/s12859-020-03908-5

Author affiliation

Department of Respiratory Sciences, University of Leicester

Version

  • VoR (Version of Record)

Published in

BMC Bioinformatics

Volume

21

Issue

1

Publisher

Springer Science and Business Media LLC

eissn

1471-2105

Acceptance date

2020-11-25

Copyright date

2020

Available date

2020-12-02

Language

en

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