Legacy data sharing to improve drug safety assessment: the eTOX project.
journal contribution
posted on 2019-07-09, 14:32 authored by F Sanz, F Pognan, T Steger-Hartmann, C Díaz, eTOX, M Cases, M Pastor, P Marc, J Wichard, K Briggs, DK Watson, T Kleinöder, C Yang, A Amberg, M Beaumont, AJ Brookes, S Brunak, MTD Cronin, GF Ecker, S Escher, N Greene, A Guzmán, A Hersey, P Jacques, L Lammens, J Mestres, W Muster, H Northeved, M Pinches, J Saiz, N Sajot, A Valencia, J van der Lei, NPE Vermeulen, E Vock, G Wolber, I ZamoraThe sharing of legacy preclinical safety data among pharmaceutical companies and its integration with other information sources offers unprecedented opportunities to improve the early assessment of drug safety. Here, we discuss the experience of the eTOX project, which was established through the Innovative Medicines Initiative to explore this possibility.
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Citation
Nature Reviews Drug Discovery, 2017, 16 (12), pp. 811-812Author affiliation
/Organisation/COLLEGE OF LIFE SCIENCES/Biological Sciences/Genetics and Genome BiologyVersion
- AM (Accepted Manuscript)
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Nature Reviews Drug DiscoveryPublisher
Nature Research (part of Springer Nature)eissn
1474-1784Copyright date
2017Available date
2019-07-09Publisher DOI
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https://www.nature.com/articles/nrd.2017.177Notes
FURTHER INFORMATION eTOX: http://www.etoxproject.eu/ eTOXlab: http://phi.imim.es/envoy/ eTOXsys: https://www.lhasalimited.org/products/etoxsys.htm SUPPLEMENTARY INFORMATION See online article: S1 (box ) ALL LINKS ARE ACTIVE IN THE ONLINE PDFLanguage
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