MIDCAN: A multiple input deep convolutional attention network for Covid-19 diagnosis based on chest CT and chest X-ray

<div>Background</div><div>COVID-19 has caused 3.34m deaths till 13/May/2021. It is now still causing confirmed cases and ongoing deaths every day.</div><div><br></div><div>Method</div><div>This study investigated whether fusing chest CT with chest X-ray can help improve the AI's diagnosis performance. Data harmonization is employed to make a homogeneous dataset. We create an end-to-end multiple-input deep convolutional attention network (MIDCAN) by using the convolutional block attention module (CBAM). One input of our model receives 3D chest CT image, and other input receives 2D X-ray image. Besides, multiple-way data augmentation is used to generate fake data on training set. Grad-CAM is used to give explainable heatmap.</div><div><br></div><div>Results</div><div>The proposed MIDCAN achieves a sensitivity of 98.10±1.88%, a specificity of 97.95±2.26%, and an accuracy of 98.02±1.35%.</div><div><br></div><div>Conclusion</div><div>Our MIDCAN method provides better results than 8 state-of-the-art approaches. We demonstrate the using multiple modalities can achieve better results than individual modality. Also, we demonstrate that CBAM can help improve the diagnosis performance.</div>