posted on 2019-07-08, 15:38authored byRachael A. Evans, Sally J. Singh
We aimed to describe the minimum important difference (MID) of the ISWT in patients with
COPD using both distribution- and anchor-based methods. Two cohorts were used (n=613)
with eligibility criteria of a clinical diagnosis of COPD, an FEV1/FVC<70%, and an ISWT
(after familiarisation) before and after a seven week course of pulmonary rehabilitation (PR).
The MID of the ISWT using the distribution method was 36.1m. The area under the curve to
discriminate between perceived ‘improvement’ or ‘no improvement’ post-PR for a change in
ISWT of 35m was 0.66 [0.58–0.73]. The MID of the ISWT is therefore between 35.0-36.1m.
Funding
RAE is funded by a National Institute for Health Research (NIHR) Clinician Scientist Fellowship (CS-2016-16-020). This research was supported by the NIHR Leicester Biomedical Research Centre - Respiratory Theme.
History
Citation
Thorax, 2019
Author affiliation
/Organisation/COLLEGE OF LIFE SCIENCES/School of Medicine/Department of Infection, Immunity and Inflammation
Version
AM (Accepted Manuscript)
Published in
Thorax
Publisher
BMJ Publishing Group, British Thoracic Society (BTS)