Monitoring cerebral hemodynamics in COVID-19 patients in the prone position

<p>Prone positioning (PP) has been used in Acute Respiratory Distress Syndrome (ARDS), including patients with COVID-19 [<a href="https://www.sciencedirect.com/science/article/pii/S0883944122000843?via=ihub#bb0005" target="_blank">1</a>]. While it improves oxygenation, the impact of PP on cerebral hemodynamics remains controversial [<a href="https://www.sciencedirect.com/science/article/pii/S0883944122000843?via=ihub#bb0010" target="_blank">2</a>,<a href="https://www.sciencedirect.com/science/article/pii/S0883944122000843?via=ihub#bb0015" target="_blank">3</a>]. Of considerable relevance, patients with COVID-19 have shown a high incidence of delirium and neurological complications, that could suggest involvement of cerebral autoregulation (CA) [<a href="https://www.sciencedirect.com/science/article/pii/S0883944122000843?via=ihub#bb0020" target="_blank">4</a>]. Above all, it is not clear how CA is affected by PP in patients with COVID-19. In a pilot prospective study, we tested the feasibility of continuously monitoring key cerebral hemodynamic parameters in COVID-19 patients undergoing PP. [Opening paragraph]</p>