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Moral and contextual dimensions of “inappropriate" antibiotic prescribing in secondary care: A three-country interview study.

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posted on 2020-05-06, 16:29 authored by carolyn Tarrant, Eva Krockow, Dilini Nakkawita, Michele Bolscher, Andrew M Colman, Edmund Chattoe-Brown, Nelun Perera, Shaheen Mehtar, David Jenkins

Overuse of broad-spectrum antibiotics in secondary care is a key contributor to the emergence and spread of antimicrobial resistance (AMR); efforts are focused on minimizing antibiotic overuse as a crucial step toward containing the global threat of AMR. The concept of overtreatment has, however, been difficult to define. Efforts to address the overuse of medicine need to be informed by an understanding of how prescribers themselves understand the problem. We report findings from a qualitative interview study of 46 acute care hospital prescribers differing in seniority from three countries: United Kingdom, Sri Lanka and South Africa. Prescribers were asked about their understanding of inappropriate use of antibiotics. Prescriber definitions of inappropriate use included relatively clear-cut and unambiguous cases of antibiotics being used “incorrectly” (e.g., in the case of viral infections). In many cases, however, antibiotic prescribing decisions were seen as involving uncertainty, with prescribers having to make decisions about the threshold for appropriate use. Decisions about thresholds were commonly framed in moral terms. Some prescribers drew on arguments about their duty to protect public health through having a high threshold for prescribing, while others made strong arguments for prioritizing risk avoidance for the patients in front of them, even at a cost of increased resistance. Notions of whether prescribing was inappropriate were also contextually dependent: high levels of antibiotic prescribing could be seen as a rational response when prescribers were working in challenging contexts, and could be justified in relation to financial and social considerations. Inappropriate antibiotic use is framed by prescribers not just in clinical, but also in moral and contextual terms; this has implications for the design and implementation of antibiotic stewardship interventions aiming to reduce inappropriate use of antibiotics globally.

Funding

This research was funded by the Global Challenges Research Fund—Grant No. ES/P004784/1 awarded by the Economic and Social Research Council (ESRC) on behalf of the Research Councils United Kingdom (RCUK).

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Citation

Tarrant C, Krockow EM, Nakkawita WMID, Bolscher M, Colman AM, Chattoe-Brown E, Perera N, Mehtar S and Jenkins DR (2020) Moral and Contextual Dimensions of “Inappropriate” Antibiotic Prescribing in Secondary Care: A Three-Country Interview Study. Front. Sociol. 5:7. doi: 10.3389/fsoc.2020.00007

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  • VoR (Version of Record)

Published in

Frontiers in Sociology

Volume

5

Issue

7

Publisher

Frontiers Media

issn

2297-7775

Acceptance date

2020-02-04

Copyright date

2020

Available date

2020-02-20

Publisher version

https://www.frontiersin.org/articles/10.3389/fsoc.2020.00007/full

Language

en

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