Non-invasive respiratory support in paediatric critical care: protocol for a cohort study emulating the FIRST-line support for Assistance in Breathing in Children (FIRST-ABC) step-up randomised clinical trial using routinely collected data from the Paediatric Intensive Care Audit Network (PICANet) database

Giallongo, Elisa; Carroll, Orlagh; Ramnarayan, Padmanabhan; Mitting, Rebecca; Seaton, Sarah; Shortt, Dermot; Mason, Alexina; Harrison, David; Grieve, Richard

Non-invasive respiratory support in paediatric critical care: protocol for a cohort study emulating the FIRST-line support for Assistance in Breathing in Children (FIRST-ABC) step-up randomised clinical trial using routinely collected data from the Paediatric Intensive Care Audit Network (PICANet) database

journal contribution

posted on 2025-10-17, 13:32 authored by Elisa Giallongo, Orlagh Carroll, Padmanabhan Ramnarayan, Rebecca Mitting, Sarah SeatonSarah Seaton, Dermot Shortt, Alexina Mason, David Harrison, Richard Grieve

<p dir="ltr">Description</p>

History

Author affiliation

University of Leicester College of Life Sciences Healthcare

Version

AM (Accepted Manuscript)

Published in

BMJ Open

Publisher

BMJ Publishing Group

issn

2044-6055

eissn

2044-6055

Copyright date

2025

Publisher DOI

https://doi.org/TBA

Notes

Embargo until publication

Language

en

Publisher version

https://bmjopen.bmj.com/

Deposited by

Dr Sarah Seaton

Deposit date

2025-10-01

Usage metrics

Keywords

Target trial emulation routinely collected data doubly robust paediatric intensive care Bayesian

Licence

CC BY 4.0