Novel insights into the mechanisms of mitotic spindle assembly by Nek kinases

Prosser, Suzanna L.; O'Regan, Laura; Fry, Andrew M.

manuscript #2015MCO0393_final author version.pdf (791.97 kB)

Novel insights into the mechanisms of mitotic spindle assembly by Nek kinases

journal contribution

posted on 2016-04-06, 10:00 authored by Suzanna L. Prosser, Laura O'Regan, Andrew M. Fry

The mitotic spindle is the apparatus upon which chromosomes are segregated during cell division. We have discovered new roles for two members of the NIMA-Related Kinase (NEK) family in different molecular processes of spindle assembly. Moreover, loss of these proteins leads to segregation errors that drive cancer progression.

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Citation

Molecular and Cellular Oncology, 2016, 3(3), e1062952

Author affiliation

/Organisation/COLLEGE OF MEDICINE, BIOLOGICAL SCIENCES AND PSYCHOLOGY/MBSP Non-Medical Departments/Molecular & Cell Biology

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AM (Accepted Manuscript)

Published in

Molecular and Cellular Oncology

Publisher

Taylor & Francis

eissn

2372-3556

Acceptance date

2015-07-06

Copyright date

2016

Available date

2018-03-27

Publisher DOI

https://doi.org/10.1080/23723556.2015.1062952

Publisher version

http://www.tandfonline.com/doi/abs/10.1080/23723556.2015.1062952

Language

en

Administrator link

https://leicester.figshare.com/account/articles/10164125

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Novel insights into the mechanisms of mitotic spindle assembly by Nek kinases

History

Citation

Author affiliation

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Published in

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eissn

Acceptance date

Copyright date

Available date

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Publisher version

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Administrator link

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