Obesity and risk of COVID-19: analysis of UK Biobank
journal contribution
posted on 2020-05-29, 09:21 authored by Thomas Yates, Cameron Razieh, Francesco Zaccardi, Melanie J Davies, Kamlesh Khunti[First paragraph] Whilst emerging evidence has suggested that those with cardiometabolic diseases are at higher risk of severe COVID-19 and
resulting complications, less is known about the relative importance of related lifestyle factors. Obesity in particular is associated with
impaired pulmonary function, a suppressed immune system and has been identified as a risk factor in previous infectious outbreaks.
Obesity also appears to be prevalent in subjects with COVID-19. However, as recently highlighted, there is a lack of information
regarding the nature of association between body mass index (BMI) and COVID-19. In order to inform this area, we investigated the association between obesity and laboratory confirmed COVID-19 within UK Biobank (application number 36371). Our hypothesis was that BMI and waist circumference would be independently associated with COVID19.
Funding
This work was supported by the NIHR Leicester Biomedical Research Centre and NIHR Applied Research Centre East Midlands. Data was analysed using UK Biobank application number 36371
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Citation
Please cite this article as: Yates T, Razieh C, Zaccardi F, Davies MJ, Khunti K, Obesity and risk of COVID-19: analysis of UK Biobank, Primary Care Diabetes (2020), doi: https://doi.org/10.1016/j.pcd.2020.05.011Version
- AM (Accepted Manuscript)
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2020Publisher DOI
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