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Peak aerobic capacity from incremental shuttle walk test in chronic kidney disease.

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journal contribution
posted on 2019-08-07, 15:10 authored by S Xenophontos, TJ Wilkinson, DW Gould, EL Watson, JL Viana, AC Smith
BACKGROUND: Assessment of cardiorespiratory fitness is an important outcome in chronic kidney disease (CKD). We aimed to develop a predictive equation to estimate peak oxygen uptake (VO2peak ) and power output (WPeak ), as measured during a cardiopulmonary exercise test (CPET), from the distance walked (DW) during the incremental shuttle walk test (ISWT). METHODS: Thirty-six non-dialysing patients with CKD [17 male, age: 61 ± 12 years, eGFR: 25±7 ml/min/1.73 m2 , body mass index (BMI): 31 ± 6 kg/m2 ] carried out laboratory-based CPET on a cycle ergometer and ISWT on two separate occasions. RESULTS: Linear regression revealed that DW/BMI was a significant predictor of VO2Peak (r = 0.78) (VO2Peak (ml/min/kg) = [0.5688 × (DW/BMI) (m)] + 11.50). No difference (p = 0.66) between CPET VO2Peak (19.9 ± 5.5 ml/min/kg) and predicted VO2Peak (19.9 ± 4.3 ml/min/kg) was observed. DW multiplied by body mass (BM) was a significant predictor of WPeak (r = 0.80) [WPeak (W) = (0.0018 × (DW × BM)) + 50.47]. No difference (p = 0.97) between CPET WPeak (116.2 ± 38.9 W) and estimated WPeak (113.9 ± 30.1 W) was seen. CONCLUSION: The present study demonstrates that VO2Peak and WPeak can be accurately estimated using the DW during an ISWT in CKD populations.

Funding

This research was co‐funded by the National Institute for Health Research (NIHR) Leicester Biomedical Research Centre (BRC) and the Stoneygate Trust. The views expressed in this publication are those of the author(s) and not necessarily those of the NHS, NIHR Leicester BRC or the Department of Health. At the time of writing this manuscript, E.L.W. was supported by a Kidney Research UK Post‐Doctoral Fellowship (PDF2–2015).

History

Citation

Journal of Renal Care, 2019

Author affiliation

/Organisation/COLLEGE OF LIFE SCIENCES/School of Medicine/Department of Infection, Immunity and Inflammation

Version

  • AM (Accepted Manuscript)

Published in

Journal of Renal Care

Publisher

Wiley for European Dialysis and Transplant Nurses Association, European Renal Care Association

eissn

1755-6686

Copyright date

2019

Publisher version

https://onlinelibrary.wiley.com/doi/full/10.1111/jorc.12293

Notes

The file associated with this record is under embargo until 12 months after publication, in accordance with the publisher's self-archiving policy. The full text may be available through the publisher links provided above.

Language

en

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