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Phacoemulsification Surgery in Eyes with Neovascular Age-Related Macular Degeneration

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posted on 2016-05-13, 11:32 authored by A. Grixti, E. Papavasileiou, Dominic Cortis, B. V. Kumar, S. Prasad
Purpose. To evaluate the visual outcomes and effect of phacoemulsification surgery on the progression of neovascular age-related macular degeneration (AMD). Methods. Retrospective, noncomparative, and interventional case series. Thirty eyes from 29 subjects with neovascular AMD treated with intravitreal antivascular endothelial growth factor (VEGF) injections who underwent phacoemulsification and had a postsurgery follow-up of 6 months were included. LogMAR best corrected visual acuity (BCVA) was assessed preoperatively; 1 month, 3 months, and 6 months postoperatively; and finally at the last visit. The frequency of anti-VEGF therapy, calculated as the number of intravitreal injections per month, and central macular thickness (CMT) before and after cataract surgery were determined. Results. Median (range) logMAR BCVA was 0.69 (0.16 to 1.32) preoperatively; 0.55 (−0.04 to 1.32) at 1 month, 0.52 (−0.1 to 1.32) at 3 months, and 0.50 (0.0 to 1.32) at 6 months postoperatively; and 0.6 (0.0 to 1.4) at final visit (P=0.0011). There was no difference in the frequency of anti-VEGF injections between the immediate 6 months before and after phacoemulsification, which was equal to 0.1667 injections per month (P=0.6377). Median CMT measured 203 μm preoperatively, which temporarily increased to 238 μm at 1 month after surgery (P=0.0093) and then spontaneously returned to baseline, measuring 212.5 μm at 3 months postoperatively (P=0.3811). Conclusion. Phacoemulsification surgery significantly improved vision in patients with neovascular AMD, with no increased need for anti-VEGF injections to keep the macula dry postoperatively.

History

Citation

ISRN Ophthalmology Volume 2014 (2014), Article ID 417603, 6 pages

Version

  • VoR (Version of Record)

Published in

ISRN Ophthalmology Volume 2014 (2014)

Publisher

Hindawi Publishing Corporation

issn

2090-5688

eissn

2090-5696

Acceptance date

2013-10-22

Copyright date

2014

Available date

2016-05-13

Publisher version

http://www.hindawi.com/journals/isrn/2014/417603/

Language

en

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