Physical activity and metabolic health: Is it all in the timing?

Regular physical activity is a cornerstone treatment for the prevention and management of multiple chronic diseases, including type 2 diabetes (T2DM) and obesity [1]. It elicits a myriad of physiological benefits across the life course, including favourable effects on body composition and markers of glycaemic control. That said, its application is often based on a one-size-fits-all approach, and there is considerable variability in how individuals respond. [Opening paragraph]