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Physical activity and nutrition in chronic kidney disease

Version 2 2023-07-12, 13:42
Version 1 2023-07-10, 11:04
journal contribution
posted on 2023-07-12, 13:42 authored by Angela Yee-Moon Wang, Daniel S March, James O Burton

Purpose of review 

Lifestyle intervention is considered a cornerstone in chronic kidney disease management and has been recommended in different international or regional clinical practice guidelines in chronic kidney disease. However, evidence was largely based on the general population. Here we summarized the latest evidence supporting lifestyle intervention in chronic kidney disease.


Recent findings 

Both observational cohort studies as well as randomized controlled trials have demonstrated health benefits with more physical activity in chronic kidney disease. There are compelling observational data supporting different health and kidney benefits with a healthy dietary pattern rich in fruits and vegetables, whole grains, plant-based foods and low in salt, low in sugar, saturated fat, red meat and ultraprocessed foods, a plant-based diet or Mediterranean diet in chronic kidney disease population. Clinical and epidemiologic studies also showed that higher 24 h urine potassium excretion (as proxy of higher dietary potassium intake) may be associated with lower blood pressure, better kidney outcomes and lower mortality in chronic kidney disease population. Randomized controlled trials also suggested that salt substitutes improved blood pressure control, reduced all-cause death and cardiovascular event risk in the general population compared with regular salt.


Summary 

Accumulating evidence supports the current recommendation of encouraging physical activity and promoting a healthy dietary pattern in chronic kidney disease patients. Whether potassium needs restriction in chronic kidney disease diet requires further review. The safety versus benefits of salt substitutes in patients with moderate and advanced chronic kidney disease warrants further investigation.

History

Author affiliation

Department of Cardiovascular Sciences, University of Leicester

Version

  • AM (Accepted Manuscript)

Published in

Current opinion in clinical nutrition and metabolic care

Volume

26

Issue

4

Pagination

385 - 392

Publisher

Ovid Technologies (Wolters Kluwer Health)

issn

1363-1950

eissn

1473-6519

Copyright date

2023

Available date

2024-06-30

Spatial coverage

England

Language

eng

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