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Recycling of a perfluoroalkylated BINOL ligand using fluorous solid-phase extraction.

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posted on 2009-12-08, 16:23 authored by John Fawcett, Eric G. Hope, Alison M. Stuart, Andrew J. West
After the asymmetric addition of allyltri-n-butyltin to benzaldehyde, a perfluoroalkylated BINOL-Sn complex was separated from the organic product using fluorous reverse phase silica gel. The lightly fluorinated ligand was then recovered by hydrolysis of the R[subscript f6]-BINOL-Sn complex with dilute hydrochloric acid and was reused three times without loss of activity or enantioselectivity.

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Citation

Green Chemistry, 2005, 7 (5), pp.316-320

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  • VoR (Version of Record)

Published in

Green Chemistry

Publisher

Royal Society of Chemistry

issn

1463-9262

eissn

1463-9270

Copyright date

2005

Available date

2009-12-08

Publisher version

http://pubs.rsc.org/en/Content/ArticleLanding/2005/GC/b418039a#!divAbstract

Language

en

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