Biovalsalva manuscript 080117-prof.pdf (213.59 kB)
Replacement of the Ascending Aorta, Aortic Root and Valve with a Novel Stentless Valved-Conduit
journal contributionposted on 2008-07-29, 15:17 authored by Kelvin K. W. Lau, Krystyna Bochenek-Klimczyk, Manuel Galiñanes, Andrzej W. Sosnowski
Purpose:- Biological valved-conduit grafts avoid the need for anticoagulation, and can exploit the excellent hemodynamic performance of stentless valves. Incorporation of sinuses of Valsalva into the neoaortic root can improve the function of the stentless valves. Description:- Here we present a novel prefabricated stentless valved-conduit incorporating sinuses of Valsalva and describe the technique of inplantation. The BioValsalva™ valved-conduit incorporates a stentless porcine aortic valve (Vascutek Elan™) suspended within a triple-layered vascular conduit (Triplex™, Vascutek, Renfrewshire, Scotland) constructed with sinuses of Valsalva. Evaluation:- The BioValsalva™ valve-conduit was used in twelve patients with aortic regurgitation due to annuloaortic ectasia unsuitable for aortic valve repair and concomitant ascending aorta aneurysm with no mortality and excellent functioned result. Conclusion:- The prefabricated, composite stentless-valved-conduit, which material is hemostatic and reduces bleeding, is easy to implant with short ischemic time, and lends itself well to a variety of insertion techniques.