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Role of the CHA<sub>2</sub>DS<sub>2</sub>-VASc score in predicting hospital stay and 90-day readmission among patients with atrial fibrillation in Syria

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posted on 2025-09-18, 11:18 authored by Ibrahim Antoun, Alamer Alkhayer, Alkassem Alkhayer, Yaman Mahfoud, Ahmed Kotb, Riyaz Somani, G André Ng, Mustafa ZakkarMustafa Zakkar
Objectives We assessed the CHA2DS2-VASc score for predicting hospital readmission risk and length of stay (LOS) in patients admitted with primary atrial fibrillation (AF). Methods This retrospective cohort study included patients with index admission for AF to Latakia’s tertiary center (May 2021–November 2023). Patients were followed 90 days to assess readmission. CHA2DS2-VASc was correlated with 90-day readmission, inpatient all-cause mortality, and LOS during index admission. Results In total, 717 patients were included; 320 (45%) were readmitted to the hospital within 90 days (58% men, 65% aged <65 years). Inpatient mortality was 4%; the median LOS was 2 days. There was an increase in the incident rate ratio (IRR) of LOS starting from a CHA2DS2-VASc of 2 (IRR: 2, 95% confidence interval [CI]: 1.7–2.2) to a score of >6 (IRR: 5, 95% CI: 1.8–10.7), compared with a score of 0. There was an incremental increase in the hazard ratio (HR) of readmission from a score of 1 (HR: 2.3, 95% CI: 1.3–4.1) to a score of >6 (HR: 41, 95% CI: 31–72) compared with a CHA2DS2-VASc of 0. Conclusion CHA2DS2-VASc could predict 90-day hospital readmission and LOS during the index admission in patients admitted with primary AF.<p></p>

Funding

Neurocardiac interaction in malignant ventricular arrhythmias and sudden cardiac death

British Heart Foundation

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Development of a successful novel technology for sudden cardiac death risk stratification for clinical use - LifeMap

Medical Research Council

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LifeMap Quality-assurance User-focussed Evaluation of Safety and Tolerability (LifeMap-QUEST) : developing LifeMap-Vest and LifeMap-Compute for exercise assessment with optimised digital ECG recording for sudden death risk stratification

National Institute for Health Research

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History

Author affiliation

College of Life Sciences Medical Sciences

Version

  • VoR (Version of Record)

Published in

Journal of International Medical Research

Volume

53

Issue

2

Pagination

3000605251314807

Publisher

SAGE Publications

issn

0300-0605

eissn

1473-2300

Copyright date

2025

Available date

2025-09-18

Spatial coverage

England

Language

en

Deposited by

Dr Ibrahim Antoun

Deposit date

2025-08-29

Data Access Statement

Data relating to this study are available upon reasonable request from the corresponding author.