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Socio‐Economic Inequalities in Stillbirth and Preterm Birth Rates Across Europe: A Population‐Based Study

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posted on 2025-08-06, 13:42 authored by Lucy SmithLucy Smith, Marianne Philibert, Sonya Scott, Maria Jose Vidal Benede, Liili Abuladze, Adela Recio Alcaide, Marina Cuttini, Maria Fernandez Elorriaga, Alex Farr, Alison Macfarlane, Ewa Mierzejewska, Jan Nijhuis, Judith Racape, Jennifer Zeitlin
<p dir="ltr">ObjectiveTo estimate socio‐economic (SES) inequalities in stillbirth and preterm birth rates across European countries using population‐based routine data.DesignCross‐sectional study of national‐level perinatal health and SES indicators (mother's education/occupation or area‐level deprivation).SettingTwenty‐four countries in the Euro‐Peristat network.PopulationSeventeen million births in 2015–2019.MethodsRates of stillbirth, singleton very preterm birth (VPB) and singleton moderate/late preterm birth (MLPB) were derived from routine national birth data collected with a common protocol.Main Outcome MeasurePercentage of excess adverse outcomes associated with SES and concentration indices.ResultsMedian rates of adverse outcomes were higher in the lowest versus highest SES groups [Stillbirth: 4.9 (interquartile range (IQR):4.30‐5.80)] versus 2.7 (IQR:2.25‐3.14) per 1000 births; VPB: 1.0 (IQR: 0.87‐1.12) versus 0.6 (IQR: 0.59‐0.66) per 100 live births; MLPB: 5.8 (IQR: 5.27‐6.40) versus 4.4 (IQR:4.13‐4.65) per 100 live births. Excess adverse outcomes associated with lower SES varied greatly, particularly for stillbirth (range−3%, 51%) versus VPB (7%, 27%) and MLPB (5%, 20%). Concentration indices further highlighted varying socio‐economic inequalities across countries. Median concentration indices were similar for countries with both lower and higher levels of adverse events, with median CIs of −0.12 for countries with both high and low levels of stillbirth.ConclusionWe identified widespread but varying inequalities between countries. These seemed to be unrelated to the rate of adverse outcomes. This suggests the need for policy strategies directly targeted to the prevention of stillbirth and preterm birth in low SES populations. Our findings demonstrate the feasibility of monitoring inequalities internationally using routine data to identify effective action.</p>

Funding

Agence Nationale de la Recherche

Horizon 2020 Framework Programme

History

Author affiliation

College of Life Sciences Population Health Sciences

Version

  • VoR (Version of Record)

Published in

BJOG: An International Journal of Obstetrics & Gynaecology

Publisher

Wiley

issn

1470-0328

eissn

1471-0528

Copyright date

2025

Available date

2025-08-06

Spatial coverage

England

Language

en

Deposited by

Professor Lucy Smith

Deposit date

2025-07-22

Data Access Statement

The data that support the findings of this study are available from the corresponding author upon reasonable request.

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