posted on 2025-08-06, 13:42authored byLucy SmithLucy Smith, Marianne Philibert, Sonya Scott, Maria Jose Vidal Benede, Liili Abuladze, Adela Recio Alcaide, Marina Cuttini, Maria Fernandez Elorriaga, Alex Farr, Alison Macfarlane, Ewa Mierzejewska, Jan Nijhuis, Judith Racape, Jennifer Zeitlin
<p dir="ltr">ObjectiveTo estimate socio‐economic (SES) inequalities in stillbirth and preterm birth rates across European countries using population‐based routine data.DesignCross‐sectional study of national‐level perinatal health and SES indicators (mother's education/occupation or area‐level deprivation).SettingTwenty‐four countries in the Euro‐Peristat network.PopulationSeventeen million births in 2015–2019.MethodsRates of stillbirth, singleton very preterm birth (VPB) and singleton moderate/late preterm birth (MLPB) were derived from routine national birth data collected with a common protocol.Main Outcome MeasurePercentage of excess adverse outcomes associated with SES and concentration indices.ResultsMedian rates of adverse outcomes were higher in the lowest versus highest SES groups [Stillbirth: 4.9 (interquartile range (IQR):4.30‐5.80)] versus 2.7 (IQR:2.25‐3.14) per 1000 births; VPB: 1.0 (IQR: 0.87‐1.12) versus 0.6 (IQR: 0.59‐0.66) per 100 live births; MLPB: 5.8 (IQR: 5.27‐6.40) versus 4.4 (IQR:4.13‐4.65) per 100 live births. Excess adverse outcomes associated with lower SES varied greatly, particularly for stillbirth (range−3%, 51%) versus VPB (7%, 27%) and MLPB (5%, 20%). Concentration indices further highlighted varying socio‐economic inequalities across countries. Median concentration indices were similar for countries with both lower and higher levels of adverse events, with median CIs of −0.12 for countries with both high and low levels of stillbirth.ConclusionWe identified widespread but varying inequalities between countries. These seemed to be unrelated to the rate of adverse outcomes. This suggests the need for policy strategies directly targeted to the prevention of stillbirth and preterm birth in low SES populations. Our findings demonstrate the feasibility of monitoring inequalities internationally using routine data to identify effective action.</p>
Funding
Agence Nationale de la Recherche
Horizon 2020 Framework Programme
History
Author affiliation
College of Life Sciences
Population Health Sciences
Version
VoR (Version of Record)
Published in
BJOG: An International Journal of Obstetrics & Gynaecology