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Structured education programme for women with polycystic ovary syndrome: a randomised controlled trial.

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posted on 2018-01-11, 11:12 authored by Hamidreza Mani, Yogini Chudasama, Michelle Hadjiconstantinou, Danielle H. Bodicoat, Charlotte Edwardson, Miles J. Levy, Laura J. Gray, Janette Barnett, Heather Daly, Trevor A. Howlett, Kamlesh Khunti, Melanie J. Davies
OBJECTIVE: To evaluate the effectiveness of a structured education programmes in women with polycystic ovary syndrome (PCOS). METHODS: Single-centre, randomised controlled trial, testing a single exposure to a group-based, face-to-face, structured education programme. Inclusion criteria were women with PCOS, aged 18-49 years inclusive and body mass index ≥23 kg/m2 for black and minority ethnicities or ≥25 kg/m2 for white Europeans. Primary outcome was step-count/day at 12 months. Secondary outcomes included indices of physical activity, cardiovascular risk factors, quality of life (QoL) and illness perception (IP). RESULTS: 161 women were included (78 control, 83 intervention); 69% white; mean age 33.4 (s.d. 7.6) years, of whom 100 (48 intervention; 52 control) attended their 12-month visit (38% attrition). 77% of the intervention arm attended the education programme. No significant change in step-count was observed at 12 months (mean difference: +351 steps/day (95% confidence interval -481, +1183); P = 0.40). No differences were found in biochemical or anthropometric outcomes. The education programme improved participants' IP in 2 dimensions: understanding their PCOS (P < 0.001) and sense of control (P < 0.01) and improved QoL in 3 dimensions: emotions (P < 0.05), fertility (P < 0.05), weight (P < 0.01) and general mental well-being (P < 0.01). DISCUSSION: A single exposure to structured education programme did not increase physical activity or improve biochemical markers in overweight and obese women with PCOS. However, providing a structured education in parallel to routine medical treatment can be beneficial for participants' understanding of their condition, reducing their anxiety and improving their QoL.


Supported by Diabetes Research Centre, University of Leicester, through funds from National Institute for Health Research (NIHR) and NIHR Collaboration for Leadership in Applied Health Research and Care – East Midlands and the NIHR Leicester – Biomedical Research Centre, a partnership between University Hospitals of Leicester NHS Trust, Loughborough University and the University of Leicester. ‘Early Career Grant’ from Society for Endocrinology (HM).



Endocrine Connections, 2018, 7 (1), pp. 26-35

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BioScientifica, European Society of Endocrinology, Society for Endocrinology





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Supplementary data This is linked to the online version of the paper at EC-17-0274