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Ekezie et al. - 2021 - The burden of chronic respiratory diseases in adults in Nepal- A systematic review.pdf (278.38 kB)

The burden of chronic respiratory diseases in adults in Nepal: A systematic review

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journal contribution
posted on 2022-09-02, 14:46 authored by Winifred Ekezie, Alex Robert Jenkins, Ian Philip Hall, Catrin Evans, Rajendra Koju, Om Prakash Kurmi, Charlotte Emma Bolton
While chronic lung disease causes substantial global morbidity and mortality, global estimates have primarily been based on broad assumptions. Specific country data from low-income countries such as Nepal are limited. This review assessed primary evidence on chronic respiratory disease burden among adults in Nepal. A systematic search was performed in June 2019 (updated May 2020) for studies through nine databases. High levels of heterogeneity deemed a narrative synthesis appropriate. Among 27 eligible studies identified, most were low-moderate quality with cross-sectional and retrospective study design. Chronic lung diseases identified were chronic obstructive pulmonary disease (COPD), asthma, bronchiectasis and restrictive lung diseases. Studies were categorised as: (i) community-based, (ii) hospital-based and (iii) comorbidity-related and disease burden. Reported disease prevalence varied widely (COPD, 1.67–14.3%; asthma, 4.2–8.9%). The prevalence of airflow obstruction was higher among rural dwellers (15.8%) and those exposed to household air pollution from domestic biomass burning as opposed to liquid petroleum gas users (Odds Ratio: 2.06). Several comorbidities, including hypertension and diabetes mellitus added to the disease burden. The review shows limited literature on lung disease burden in Nepal. Publications varied in terms of overall quality. Good quality research studies with prospective cohorts related to respiratory conditions are required.

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Citation

Ekezie, W., Jenkins, A. R., Hall, I. P., Evans, C., Koju, R., Kurmi, O. P., & Bolton, C. E. (2021). The burden of chronic respiratory diseases in adults in Nepal: A systematic review. Chronic Respiratory Disease. https://doi.org/10.1177/1479973121994572

Author affiliation

Department of Health Sciences

Version

  • VoR (Version of Record)

Published in

CHRONIC RESPIRATORY DISEASE

Volume

18

Pagination

(20)

Publisher

SAGE PUBLICATIONS LTD

issn

1479-9723

eissn

1479-9731

Acceptance date

2021-01-23

Copyright date

2021

Available date

2022-09-02

Language

English

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