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The current state of molecular testing in the treatment of patients with solid tumors, 2019.pdf (615.35 kB)

The current state of molecular testing in the treatment of patients with solid tumors, 2019.

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journal contribution
posted on 2019-10-17, 08:56 authored by WS El-Deiry, RM Goldberg, H-J Lenz, AF Shields, GT Gibney, AR Tan, J Brown, B Eisenberg, EI Heath, S Phuphanich, E Kim, AJ Brenner, JL Marshall
The world of molecular profiling has undergone revolutionary changes over the last few years as knowledge, technology, and even standard clinical practice have evolved. Broad molecular profiling is now nearly essential for all patients with metastatic solid tumors. New agents have been approved based on molecular testing instead of tumor site of origin. Molecular profiling methodologies have likewise changed such that tests that were performed on patients a few years ago are no longer complete and possibly inaccurate today. As with all rapid change, medical providers can quickly fall behind or struggle to find up-to-date sources to ensure he or she provides optimum care. In this review, the authors provide the current state of the art for molecular profiling/precision medicine, practice standards, and a view into the future ahead.

Funding

Marion L. Hartley, PhD, provided invaluable writing and editing support, table and bibliography creation, author coordination, and article organization. These medical writing activities were supported by Caris Life Sciences.

History

Citation

CA: A Cancer Journal for Clinicians, 2019, 69 (4), pp. 305-343

Author affiliation

/Organisation/COLLEGE OF LIFE SCIENCES

Version

  • VoR (Version of Record)

Published in

CA: A Cancer Journal for Clinicians

Publisher

Wiley for American Cancer Society

eissn

1542-4863

Copyright date

2019

Available date

2019-10-17

Publisher version

https://onlinelibrary.wiley.com/doi/full/10.3322/caac.21560

Notes

Additional supporting information may be found online in the Supporting Information section at the end of the article.

Language

en

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