The greatest health problem of the Middle Ages? Estimating the burden of disease in medieval England

<div>Objective</div><div>To identify the major health problems of the Middle Ages. Bubonic plague is often considered the greatest health disaster in medieval history, but this has never been systematically investigated.</div><div><br></div><div>Materials</div><div>We triangulate upon the problem using (i) modern WHO data on disease in the modern developing world, (ii) historical evidence for England such as post-medieval Bills of Mortality, and (iii) prevalences derived from original and published palaeopathological studies.</div><div><br></div><div>Methods</div><div>Systematic analysis of the consequences of these health conditions using Disability Adjusted Life Years (DALYs) according to the Global Burden of Disease methodology.</div><div><br></div><div>Results</div><div>Infant and child death due to varied causes had the greatest impact upon population and health, followed by a range of chronic/infectious diseases, with tuberculosis probably being the next most significant one.</div><div><br></div><div>Conclusions</div><div>Among medieval health problems, we estimate that plague was probably 7th–10th in overall importance. Although lethal and disruptive, it struck only periodically and had less cumulative long-term human consequences than chronically endemic conditions (e.g. bacterial and viral infections causing infant and child death, tuberculosis, and other pathogens).</div><div><br></div><div>Significance</div><div>In contrast to modern health regimes, medieval health was above all an ecological struggle against a diverse host of infectious pathogens; social inequality was probably also an important contributing factor.</div><div><br></div><div>Limitations</div><div>Methodological assumptions and use of proxy data mean that only approximate modelling of prevalences is possible.</div><div><br></div><div>Suggestions for further research</div><div>Progress in understanding medieval health really depends upon understanding ancient infectious disease through further development of biomolecular methods.</div>