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The Microcirculation in Sepsis and its Measurement - v0 4.pdf (313.74 kB)

The microcirculation and its measurement in sepsis

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journal contribution
posted on 2018-05-02, 13:40 authored by Matthew Charlton, Mark Sims, Tim Coats, Jonathan P. Thompson
The microcirculation describes the smallest elements of the cardiovascular conducting system and is pivotal in the maintenance of homeostasis. Microcirculatory dysfunction is present early in the pathophysiology of sepsis, with the extent of microcirculatory derangement relating to disease severity and prognosis in ICU patients. However, at present microcirculatory function is not routinely monitored at the bedside. This article describes the pathophysiology of microcirculatory derangements in sepsis, methods of its measurement and evidence to support their clinical use.

History

Citation

Journal of the Intensive Care Society, 2017, 18 (3), pp. 221-227

Author affiliation

/Organisation/COLLEGE OF LIFE SCIENCES/School of Medicine/Department of Cardiovascular Sciences

Version

  • AM (Accepted Manuscript)

Published in

Journal of the Intensive Care Society

Publisher

SAGE Publications

issn

1751-1437

Copyright date

2016

Available date

2018-05-02

Publisher version

http://journals.sagepub.com/doi/10.1177/1751143716678638

Language

en

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