The regiospecific Fischer Indole reaction in choline chloride.2ZnCl[subscript 2] with product isolation by direct sublimation from the ionic liquid
journal contribution
posted on 2009-12-08, 16:23 authored by Raul Calderon Morales, Vasuki Tambyrajah, Paul R. Jenkins, David L. Davies, Andrew P. AbbottThe Fischer indole synthesis occurs in high yield with one equivalent of the ionic liquid choline chloride·2ZnCl[subscript 2]; exclusive formation of 2,3-disubstituted indoles is observed in the reaction of alkyl methyl ketones, and the products readily sublime directly from the ionic liquid.
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Citation
Chemical Communications, 2004, pp.158-159Version
- VoR (Version of Record)
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Chemical CommunicationsPublisher
The Royal Society of Chemistryissn
1359-7345eissn
1364-548XAvailable date
2009-12-08Publisher DOI
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http://pubs.rsc.org/en/Content/ArticleLanding/2004/CC/b313655h#!divAbstractLanguage
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